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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGL
All Species:
7.58
Human Site:
T334
Identified Species:
15.15
UniProt:
P35573
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35573
NP_000019.2
1532
174764
T334
S
D
P
N
Q
H
L
T
I
I
Q
D
P
E
Y
Chimpanzee
Pan troglodytes
XP_524777
1532
174746
T334
S
D
P
N
Q
H
L
T
I
I
Q
D
P
E
Y
Rhesus Macaque
Macaca mulatta
XP_001106231
1532
174684
K334
S
D
P
N
Q
H
L
K
I
I
Q
D
P
E
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074795
1532
174269
K334
S
E
P
K
E
H
L
K
I
I
Q
D
P
E
Y
Rat
Rattus norvegicus
NP_001102034
1532
174314
K334
S
E
P
K
E
H
L
K
I
I
Q
D
P
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512323
1163
131293
S58
E
G
N
T
P
L
I
S
Q
Y
F
T
F
P
Y
Chicken
Gallus gallus
XP_422317
1532
174660
Q335
S
D
P
N
Q
H
L
Q
I
V
Q
D
P
D
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696194
1052
117860
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726062
1629
183200
Q447
E
C
R
F
Q
E
I
Q
L
I
Q
D
P
Q
Y
Honey Bee
Apis mellifera
XP_394961
1549
176545
K333
S
K
T
S
E
D
I
K
I
I
Q
D
S
K
F
Nematode Worm
Caenorhab. elegans
NP_496984
1467
165910
E321
P
L
D
G
E
D
V
E
I
E
Q
D
L
E
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06625
1536
174953
S347
S
D
F
V
K
L
A
S
F
V
K
D
N
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.6
N.A.
N.A.
91.9
92.1
N.A.
67.6
81.7
N.A.
53.3
N.A.
45.2
49.9
44.2
N.A.
Protein Similarity:
100
100
99.2
N.A.
N.A.
96.6
96.4
N.A.
72
91.5
N.A.
61.3
N.A.
61.4
66.6
62
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
73.3
66.6
N.A.
6.6
80
N.A.
0
N.A.
40
33.3
26.6
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
86.6
86.6
N.A.
20
93.3
N.A.
0
N.A.
60
66.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
42
9
0
0
17
0
0
0
0
0
84
0
9
0
% D
% Glu:
17
17
0
0
34
9
0
9
0
9
0
0
0
50
0
% E
% Phe:
0
0
9
9
0
0
0
0
9
0
9
0
9
0
17
% F
% Gly:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
25
0
67
59
0
0
0
0
0
% I
% Lys:
0
9
0
17
9
0
0
34
0
0
9
0
0
9
0
% K
% Leu:
0
9
0
0
0
17
50
0
9
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
34
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
0
50
0
9
0
0
0
0
0
0
0
59
9
0
% P
% Gln:
0
0
0
0
42
0
0
17
9
0
75
0
0
9
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
67
0
0
9
0
0
0
17
0
0
0
0
9
0
0
% S
% Thr:
0
0
9
9
0
0
0
17
0
0
0
9
0
0
9
% T
% Val:
0
0
0
9
0
0
9
0
0
17
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
59
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _